Award
NIH Reporter #5R01NS051709-19
TNF in Injury and Repair Processes Following Traumatic SCI
Recipient
George Washington University, Washington, DC
Award Amount
$494,226.00
Ceiling
$494,226.00
Awarded
July 22, 2026
Identifier
5R01NS051709-19
Research project funded by NINDS to study TNF signaling pathways in chronic neuropathic pain and develop effective therapies considering sex differences.
Description
This project focuses on understanding the mechanisms of chronic neuropathic pain and developing effective therapies, with an emphasis on sex differences and neuroinflammation pathways. The project aims to investigate divergent mechanisms through which TNFR1 and TNFR2 signaling pathways govern the development and recovery from chronic pain, respectively, and to develop therapies effective in both women and men.