Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK113788-07
Exploring the role, regulation, and antimicrobial function of Paneth cell peptides PYY and NPY in maintaining gut microbial commensalism and innate immune defense
Recipient
University of Chicago, Chicago, IL, United States
Award Amount
$686,715.00
Ceiling
$686,715.00
Awarded
February 16, 2026
Identifier
5R01DK113788-07
Research project funded by NIDDK to study the role and regulation of Paneth cell peptides PYY and NPY in gut microbial balance and innate immune defense.
Description
The project investigates Paneth Cell anti-microbial peptides PYY and NPY, which are involved in maintaining gut microbial balance and immune defense. The study aims to define regulation pathways and antimicrobial spectra of these peptides using in vivo and in vitro approaches.