Award
National Institute of Diabetes and Digestive and Kidney Diseases 5K23DK128567-05
Personalizing Therapies for Acute Kidney Injury in Cirrhosis
Recipient
Massachusetts General Hospital
Award Amount
$196,169.00
Ceiling
$196,169.00
Awarded
April 02, 2026
Identifier
5K23DK128567-05
A research project funded by the National Institute of Diabetes and Digestive and Kidney Diseases to improve treatment for acute kidney injury in cirrhosis by personalizing intravenous albumin dosing based on intravascular volume measurements.
Description
This project focuses on personalizing therapy for AKI in cirrhosis using novel volume measurement techniques and subphenotyping to improve patient outcomes. The project aims to define predictors of renal response and personalize IV albumin dosing using intravascular volume measurement, including Point of Care Ultrasound (POCUS), to optimize treatment and outcomes.