Award
NIH Reporter #1F31ES038021-01
Perfluorooctanoic acid: a potential environmental modulator of susceptibility to gestational diabetes mellitus
Recipient
University of Rochester, Rochester, NY
Award Amount
$49,538.00
Ceiling
$49,538.00
Awarded
August 12, 2025
Identifier
1F31ES038021-01
Research project studying the impact of perfluorooctanoic acid on maternal vitamin B6 levels and susceptibility to gestational diabetes mellitus, focusing on environmental and genetic factors.
Description
This research explores how perfluorooctanoic acid (PFOA), a persistent endocrine-disrupting chemical, modulates maternal vitamin B6 and susceptibility to gestational diabetes mellitus (GDM). The study aims to identify environmental and genetic factors affecting maternal vitamin B6 levels and investigate PFOA's effects on maternal pancreatic beta cell proliferation, critical for maintaining healthy glucose levels during pregnancy.