Award
NIH Reporter #5R01AR083407-03
Regulation of inflammation by the ubiquitin proteasome pathway
Recipient
New York University School of Medicine, NY, United States
Award Amount
$576,603.00
Ceiling
$576,603.00
Awarded
January 14, 2026
Identifier
5R01AR083407-03
This NIH-funded project studies VEXAS syndrome, an inflammatory disease caused by UBA1 mutations, using mouse models to understand disease mechanisms and test therapies.
Description
The project aims to utilize mouse models to define cellular and molecular mechanisms of VEXAS syndrome, focusing on inflammation pathways, and exploring potential therapies using small molecules.