Award
NIH Reporter #5R33NS126626-04
Investigational WNT-pathway modulators for the treatment and prevention of drug-resistant seizures
Recipient
University of Washington, Seattle, WA
Award Amount
$190,646.00
Ceiling
$190,646.00
Awarded
August 31, 2026
Identifier
5R33NS126626-04
A research project funded by the National Institute of Neurological Disorders and Stroke to study investigational WNT-pathway modulators for treating and preventing drug-resistant seizures, aiming to develop therapies that can prevent or delay epilepsy onset.
Description
This project aims to fully characterize the anticonvulsant and disease-modifying potential of two investigational treatments targeting the WNT signaling pathway, with the goal of developing therapies that can prevent or delay the onset of epilepsy. The project focuses on epilepsy research, specifically on investigational treatments targeting the WNT pathway, evaluating efficacy, pharmacokinetics, and disease-modifying potential in rodent models.