Award
National Institute on Drug Abuse 1U01DA063352-01
Development of the anti-fentanyl monoclonal antibody, CSX-1004, for prophylaxis against fentanyl and fentanyl analog overdose
Recipient
National Institute on Drug Abuse (NIDA)
Award Amount
$2,612,736.00
Ceiling
$2,612,736.00
Awarded
September 02, 2025
Identifier
1U01DA063352-01
Award for development of CSX-1004, an anti-fentanyl monoclonal antibody, to prevent fentanyl overdose, funded by NIDA with a $2.6M budget, based in San Jose, CA, from 2025 to 2028.
Description
The project involves clinical studies of a monoclonal antibody (CSX-1004) targeting fentanyl and analogs. The goal is to evaluate safety, pharmacokinetics, and efficacy to prevent respiratory depression. The project aims to prepare for FDA meetings and eventual BLA submission. Funding is provided by the National Institute on Drug Abuse (NIDA). The project is located in San Jose, CA. The project duration is from September 15, 2025, to July 31, 2028.