Award
National Institute of Neurological Disorders and Stroke 5R01NS140701-02
Cortical dystonia of prematurity
Recipient
Washington University in Saint Louis, MO
Award Amount
$594,604.00
Ceiling
$594,604.00
Awarded
June 19, 2026
Identifier
5R01NS140701-02
Award for research on cortical dystonia of prematurity, investigating sensorimotor PVINs as treatment targets, funded by NIH with an amount of $594,604 for fiscal year 2026.
Description
The project focuses on investigating sensorimotor cortex parvalbumin-positive interneurons as a new cortical treatment target for dystonia following preterm birth. The project involves longitudinal assessment of sensorimotor PVIN number, cortical oscillatory activity, and dystonic behavior in mice. The study aims to establish the role of sensorimotor PVINs in dystonia prediction, pathophysiology, and treatment. The project is funded by NIH grant PA-20-185 and conducted by Washington University in Saint Louis, MO.