Award
National Institute of General Medical Sciences 5R01GM155691-02
Regulation of ceramide-1-phosphate metabolism in cell signaling networks
Recipient
UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA
Award Amount
$353,430.00
Ceiling
$353,430.00
Awarded
July 24, 2026
Identifier
5R01GM155691-02
NIH grant awarded to study the role of ceramide-1-phosphate metabolism in cell signaling and metabolic reprogramming, with implications for disease therapeutics.
Description
This grant supports research on sphingolipid signaling, mitochondrial function, and metabolic reprogramming with potential applications in disease therapeutics. The study focuses on ceramide-1-phosphate (C1P), produced by ceramide kinase (CERK), as a key regulator of metabolic reprogramming affecting mitochondrial function, signaling pathways, and lipid droplet biosynthesis.