Award
National Institute of Neurological Disorders and Stroke 1R01NS144659-01
Exploring activity-dependent regulation of intra and intercellular mitochondrial transport in astrocytes
Recipient
Washington University, Saint Louis, MO, United States
Award Amount
$488,232.00
Ceiling
$488,232.00
Awarded
July 30, 2025
Identifier
1R01NS144659-01
Research project funded by NINDS to study mitochondrial transport in astrocytes and its role in neuronal support and neurodegenerative disease mechanisms.
Description
This project leverages Drosophila models to study how astrocytes position mitochondria near synapses and transport mitochondria to neurons, aiming to identify cellular mechanisms and cues involved. The goal is to better understand astrocyte-neuron metabolic coupling to alleviate circuit dysfunction in neurodegenerative diseases.