Award
NIH Reporter #5P01AI186771-02
Sequencing and sample core: genetic errors of immunity
Recipient
Washington University, Saint Louis, MO, United States
Award Amount
$456,329.00
Ceiling
$456,329.00
Awarded
April 03, 2026
Identifier
5P01AI186771-02
This award funds a project to study genetic errors of immunity through advanced sequencing techniques, aiming to identify genetic causes of immune dysregulation syndromes and understand variable disease penetrance by analyzing samples from human subjects.
Description
The project involves sequencing and analysis of genetic errors related to immunity, focusing on understanding genetic lesions, penetrance, and molecular signatures using advanced sequencing techniques. It aims to streamline datasets for enrolled patients and families by storing samples and sequencing results, sharing data with bioinformatics core and associated projects to increase efficiency of data collection and analysis.