Award
National Institute on Aging 3R01AG058063-09S2
Harnessing Diverse Bioinformatic Approaches To Repurpose Drugs For Alzheimers Disease And Related Dementias
Recipient
Massachusetts General Hospital
Award Amount
$115,560.00
Ceiling
$115,560.00
Awarded
July 08, 2026
Identifier
3R01AG058063-09S2
A NIH-funded project by Massachusetts General Hospital to use bioinformatics and electronic health records to repurpose FDA-approved drugs for Alzheimer's disease treatment, promoting open science and data sharing.
Description
This project aims to repurpose existing FDA-approved drugs to accelerate proof-of-concept and therapeutic clinical trials for Alzheimer's disease using bioinformatics, machine learning, systems pharmacology, and electronic health records analysis. The project involves data-driven and hypothesis-testing approaches to identify and validate drug candidates and pathways involved in Alzheimer's disease progression. The data and findings will be shared openly to promote further clinical and translational studies.