Award
National Heart, Lung, and Blood Institute 5R01HL147290-08
Pathogenesis of lung injury mediated by lung-restricted antibodies
Recipient
Northwestern University
Award Amount
$658,821.00
Ceiling
$658,821.00
Awarded
April 02, 2026
Identifier
5R01HL147290-08
The award supports research on the immune mechanisms of primary graft dysfunction in lung transplant patients, investigating lung-restricted autoantibodies, monocyte activation, and immune complex formation to improve transplant outcomes.
Description
This project aims to elucidate the immune mechanisms underlying primary graft dysfunction in lung transplant recipients, focusing on autoantibody interactions, monocyte activation, and immune complex formation to develop targeted therapies.