Award
National Institute of Allergy and Infectious Diseases 5R01AI191440-02
Dissecting innate immune control of intestinal and systemic Yersinia infection
Recipient
University of Pennsylvania
Award Amount
$1,038,050.00
Ceiling
$1,038,050.00
Awarded
February 13, 2026
Identifier
5R01AI191440-02
NIH-funded research project investigating immune mechanisms controlling Yersinia infection, focusing on TNF and IL-1 pathways and their role in infection control and dissemination.
Description
This project aims to define TNF- and IL-1-dependent mechanisms that regulate pyogranuloma formation and control of Yersinia infection and dissemination dynamics, providing new insights into host defense against bacterial infection.