Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK054937-27
Transcriptional Networks Controlling Erythroid Differentiation
Recipient
Children's Hospital of Philadelphia
Award Amount
$752,242.00
Ceiling
$752,242.00
Awarded
March 23, 2026
Identifier
5R01DK054937-27
This NIH grant supports research on the role of Ldb1 protein in erythroid cell gene regulation and chromatin organization, using advanced chromatin mapping and protein degradation techniques to understand gene expression dynamics.
Description
The project focuses on studying the function of the protein Ldb1 in chromosomal organization and gene regulation in erythroid cells. The project involves high-resolution chromatin mapping, acute protein degradation, and analysis during cell cycle transitions. The project aims to provide a comprehensive view of chromatin architecture and gene expression dynamics.