Award

National Institute on Aging 5R01AG075927-04

Whole Genome Sequencing and Admixture Analyses of Neuropathologic Traits in White, Black, and Latino Americans and Brazilians

Recipient

Rush University Medical Center

Award Amount

$2,290,856.00

Ceiling

$2,290,856.00

Awarded

July 31, 2026

Identifier

5R01AG075927-04

This award funds a project to generate and analyze whole genome sequencing data from diverse populations to study Alzheimer's Disease and related dementias, aiming to identify molecular drivers and share data with the research community.

Description

The proposed project will deliver a comprehensive set of whole genome sequencing (WGS) data from individuals of African, European, and Native Brazilian ancestry, and analyze their associations with Alzheimer’s Disease and Related Dementias (AD/ADRD) clinical and neuropathologic traits. The data will be shared with the aging and dementia research community to have a sustained impact.

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