Award
NIH Reporter #1F31AI197980-01
Human retrovirus assembly interplay with the actin cortex
Recipient
University of Minnesota
Award Amount
$48,621.00
Ceiling
$48,621.00
Awarded
April 21, 2026
Identifier
1F31AI197980-01
The project studies how actin cortex properties affect HIV-1, HIV-2, and HTLV-1 particle assembly, with the aim of addressing knowledge gaps and informing antiviral target identification and therapeutic development.
Description
This project investigates how the cellular actin cortex relates to the formation of human retrovirus particle assembly sites, including the trafficking and assembly of Gag-genomic RNA complexes.