Award
The Ohio State University 5R01AA031056-03
The JNK2-NLRP3 nexus in atrial fibrillation and its anti-AF therapeutic potentials
Recipient
Ohio State University
Award Amount
$591,477.00
Ceiling
$591,477.00
Awarded
May 01, 2026
Identifier
5R01AA031056-03
Research project awarded to Ohio State University to study the role of JNK2-NLRP3 in atrial fibrillation and develop potential therapies, led by Professor Xun Ai with NIH support.
Description
The project focuses on the role of JNK2-NLRP3 in atrial fibrillation and explores therapeutic potentials. The project involves multidisciplinary approaches including molecular biochemistry, electrophysiology, and animal models. It aims to establish a novel link between JNK2-NLRP3 and inflammation pathways in AF pathogenesis. The project is led by Professor Xun Ai at Ohio State University and is supported by the NIH grant PA-20-185.