Award
National Cancer Institute 11309547
Functional consequences of high glucose culture on adoptive T cell therapies for cancer
Recipient
National Cancer Institute (NCI)
Award Amount
$55,114.00
Ceiling
$55,114.00
Awarded
April 09, 2026
Identifier
11309547
This award funds research on the effects of high glucose culture conditions on T cell therapies for cancer, aiming to improve CAR-T cell therapy effectiveness through mechanistic studies.
Description
The project focuses on understanding how high glucose levels in culture media affect T cell function and glycosylation, with implications for CAR-T cell therapy. It involves mechanistic studies on protein glycosylation and T cell signaling pathways, with translation to human CAR-T models.