Award
National Heart, Lung, and Blood Institute 11332470
Leveraging multi-omics for endotyping to identify subtypes and mechanisms of cardiometabolic diseases
Recipient
Vanderbilt University Medical Center
Award Amount
$157,550.00
Ceiling
$157,550.00
Awarded
June 08, 2026
Identifier
11332470
This NIH/NHLBI funded project uses multi-omics data to identify subtypes and mechanisms of cardiometabolic diseases through advanced modeling and clustering techniques.
Description
The project focuses on using multi-omics approaches to identify subtypes and mechanisms of cardiometabolic diseases, leveraging data from BioVU, TOPMed, and bariatric surgery cohorts. The project aims to develop genetically predicted levels of transcriptome, proteome, and metabolome, and to create clusters representing diseases and responses to treatment. The study involves advanced network modeling and clustering techniques. The project is funded by NIH/NHLBI under PA-20-190. The principal investigator is Minoo Bagheri, Research Instructor at Vanderbilt University Medical Center.