Award

NIH Reporter #5R01MH134797-03

Role of the brain-immune axis in neuropsychiatric disease

Recipient

University of Pennsylvania, Philadelphia, PA, United States

Award Amount

$407,857.00

Ceiling

$407,857.00

Awarded

January 14, 2026

Identifier

5R01MH134797-03

Research project funded by the National Institute of Mental Health to investigate the brain-immune axis in neuropsychiatric disease, particularly in 22q11.2 deletion syndrome, aiming to develop therapeutic strategies.

Description

This project studies how the brain vasculature interacts with the immune system to impact the brain and behavior during development and in response to environmental factors, focusing on 22q11.2 deletion syndrome as a model for neuropsychiatric disorders. The research aims to understand and correct abnormalities in the brain-immune axis to treat behavioral deficits.

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