# NIH Reporter #5R01CA289500-03

Overcoming Therapy Resistance in SCLC

**Recipient:** UT Southwestern Medical Center

**Award Amount:** $498,927.00
**Ceiling:** $498,927.00

**Awarded:** February 06, 2026

**Identifier:** 5R01CA289500-03

The project studies a telomerase-targeting molecule as a potential way to improve treatment of small cell lung cancer, including in combination with radiation or chemotherapy. It aims to understand effects on tumor immunity and resistance to current treatments.

### Description

NIH-funded project investigating how targeting telomerase can sensitize small cell lung cancer to radiation or chemotherapy, induce immune responses, and overcome resistance to existing treatments.

[View original record](https://reporter.nih.gov/search/0ftClcwKYUOEq8QKPKx2lA/project-details/11286788)