Award
National Institute of Neurological Disorders and Stroke 5R01NS138127-02
Molecular basis for functional S1PR1 antagonists in the treatment of comorbid migraine and temporomandibular disorders
Recipient
University of Maryland Baltimore
Awarded
August 21, 2025
Identifier
5R01NS138127-02
NIH grant awarded to University of Maryland Baltimore for research on S1PR1 antagonists as treatment for migraine and temporomandibular disorders.
Description
This is a NIH grant project focusing on molecular mechanisms and therapeutic targets for migraine and TMD, involving multidisciplinary research approaches including behavioral, molecular pharmacology, electrophysiology, genetics, biochemistry, immunohistochemistry, and mass spectrometry. The project aims to validate S1PR1 as a therapeutic target and explore downstream inflammatory mechanisms.