Award
NIH Reporter #1ZIAAI001405-01
Disruption of Oral Immune Tolerance by Respiratory Infections: Mechanisms of LungGut Immune Crosstalk
Recipient
National Institute of Allergy and Infectious Diseases (NIAID), United States
Award Amount
$458,767.00
Ceiling
$458,767.00
Awarded
April 27, 2024
Identifier
1ZIAAI001405-01
The awarded project studies the impact of respiratory infections on oral immune tolerance, revealing how lung inflammation can disrupt tolerance to food antigens and promote food allergy development.
Description
This project investigates how respiratory infections affect the establishment of oral tolerance to food antigens, focusing on the mechanisms by which lung inflammation can break oral tolerance and initiate food allergy, particularly during early childhood.