Award
National Eye Institute 5R01EY032073-05
Staphylococcus Biology in Ocular Infections
Recipient
University of Oklahoma Health Sciences Center
Award Amount
$362,500.00
Ceiling
$362,500.00
Awarded
August 04, 2025
Identifier
5R01EY032073-05
NIH grant awarded to University of Oklahoma Health Sciences Center to study Staphylococcus aureus mechanisms in ocular infections and develop preventive therapeutics.
Description
This project investigates the pathogenic mechanisms by which Staphylococcus aureus initiates ocular infections, aiming to identify targets for prevention and treatment. It focuses on adhesins and toxins involved in tissue adherence, barrier breach, and immune evasion, using mutant strains and infection models, with potential development of therapeutics to prevent infection and preserve vision.