Award
National Institute of Allergy and Infectious Diseases 1R01AI192838-01
Deciphering Borrelia burgdorferi RpoS regulatory networks in ticks and mammals
Recipient
University of Connecticut School of Medicine
Award Amount
$640,129.00
Ceiling
$640,129.00
Awarded
September 01, 2025
Identifier
1R01AI192838-01
This NIH-funded research project aims to understand the gene regulation mechanisms of Borrelia burgdorferi during its lifecycle in ticks and mammals, focusing on the RpoS regulatory networks.
Description
Research project to define how BosR and PlzA modulate transcription by RNA polymerase-RpoS and assess other regulatory factors in tick- and mammalian-phase RpoS regulons related to Borrelia burgdorferi, the causative agent of Lyme disease.