Award
NIH Reporter #1R35GM164086-01
Function-selective modulators of multifunctional hub proteins
Recipient
University of California, San Francisco
Award Amount
$551,000.00
Ceiling
$551,000.00
Awarded
September 03, 2026
Identifier
1R35GM164086-01
This award funds research to develop molecular glues and sensors to selectively modulate protein-protein interactions involving multifunctional hub proteins, advancing understanding of protein dynamics and disease mechanisms.
Description
The project aims to develop tools to manipulate protein interactions, especially hub proteins. Focus on molecular glues and VCP conformational sensors. The research is supported by NIGMS and involves advanced biochemical and proteomic techniques.