Award
National Institute of General Medical Sciences 1R35GM159997-01
Developing and Discovering Covalent Inhibitors through Fragmentation-First Experimentation
Recipient
Daniel James Blair
Award Amount
$2,503,299.00
Ceiling
$2,503,299.00
Awarded
August 11, 2025
Identifier
1R35GM159997-01
Award to develop modular frameworks for high-throughput synthesis and ranking of covalent inhibitors using fragmentation-first experimentation to accelerate drug discovery for infectious diseases and cancer.
Description
This project aims to develop modular frameworks for high-throughput synthesis and ranking of covalent inhibitors, leveraging fragmentation-first experimentation to accelerate drug discovery, particularly targeting infectious diseases and cancer.