Award
National Institute of General Medical Sciences 5R35GM152029-03
Riboswitches and their application to RNA visualization and transcription factor interactions with the transcriptome
Recipient
University of Colorado, Boulder, CO, United States
Award Amount
$597,408.00
Ceiling
$597,408.00
Awarded
February 02, 2026
Identifier
5R35GM152029-03
This award funds a research project at the University of Colorado, Boulder to study riboswitches and their applications in RNA visualization and transcription factor interactions, aiming to advance understanding of RNA-small molecule interactions and develop new RNA imaging tools.
Description
A research project focused on understanding riboswitches, developing RNA tagging tools, and investigating RNA-protein interactions. The project aims to develop a molecular understanding of how mRNA interacts with small molecules and how these interactions drive biological processes, develop novel platforms for tagging RNAs with fluorophores for imaging in live mammalian cells, and investigate how classical transcription factors interact with the transcriptome.