# NIH Reporter #5U19AI174998-04

mVACS--mRNA Vaccines for C. difficile Suppression

**Recipient:** University of Pennsylvania, Department of Microbiology/Immunology/Virology

**Award Amount:** $1,529,954.00
**Ceiling:** $1,529,954.00

**Awarded:** May 28, 2026

**Identifier:** 5U19AI174998-04

Funding supports a University of Pennsylvania program developing and evaluating modified mRNA vaccines against C. difficile, including research into vaccine targets, formulations, and immune responses.

### Description

The mVACS program aims to design and implement modified mRNA vaccines to mitigate or eliminate Clostridioides difficile infection. It includes vaccine development, antigen discovery, immunology, and administrative, genomics, and clinical cores.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11321583)