Award
National Institute of General Medical Sciences 5R01GM124143-09
Nuclear Pore Complexes As Scaffolds For Genome Architecture And Epigenetic Maintenance
Recipient
San Diego State University, San Diego, CA, United States
Award Amount
$325,532.00
Ceiling
$325,532.00
Awarded
August 19, 2025
Identifier
5R01GM124143-09
This project studies the role of Nuclear Pore Complex components in genome architecture and gene regulation, focusing on mechanisms like enhancer-promoter looping and transcriptional memory, to understand developmental and pathological processes.
Description
The project aims to define molecular mechanisms by which Nuclear Pore Complex (NPC) components (Nups) organize genome architecture and regulate gene expression, with implications for understanding pathologies and developmental processes linked to the NPC.