Award
National Cancer Institute 5R01CA259307-05
Biological Indicators of Racial Disparity in Ameloblastoma Recurrence
Recipient
University of Pennsylvania
Award Amount
$371,719.00
Ceiling
$371,719.00
Awarded
December 10, 2025
Identifier
5R01CA259307-05
Research project funded by NIH/NCI to study racial disparities in ameloblastoma recurrence by investigating autophagic and bioenergetic pathways as biomarkers and mechanisms, aiming to develop prognostic biomarkers and targeted therapies.
Description
The project aims to identify biological markers and mechanisms underlying racial disparities in ameloblastoma recurrence, focusing on autophagic processes and bioenergetic recycling. It involves analysis of autophagic proteins, bioenergetic recycling, and racial disparity in tumor recurrence, including tissue cohorts and cell line studies, to develop prognostic biomarkers and targeted therapies.