Award
National Institute of Allergy and Infectious Diseases 5R01AI167880-03
Redox Regulation of DksA-dependent Borrelia burgdorferi infectivity
Recipient
Creighton University
Award Amount
$430,347.00
Ceiling
$430,347.00
Awarded
July 29, 2025
Identifier
5R01AI167880-03
This award funds research on how Borrelia burgdorferi senses oxidative stress via DksA to regulate gene expression and virulence, aiming to improve understanding and prevention of Lyme disease.
Description
Research project focusing on the molecular mechanisms of Borrelia burgdorferi in Lyme disease, specifically the role of DksA in sensing oxidative stress and regulating virulence gene expression to inform strategies to prevent tick-borne infections.