Award
NIH Reporter #5R01MH128277-05
Sensitive periods for interneuron development supporting cognitive flexibility
Recipient
NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY, USA
Award Amount
$562,115.00
Ceiling
$562,115.00
Awarded
July 10, 2026
Identifier
5R01MH128277-05
Research project funded by NIMH to study the role of specific interneurons in the prefrontal cortex in supporting cognitive flexibility and how developmental disruptions affect adult cognition.
Description
This project investigates how GABAergic interneurons in the prefrontal cortex support cognitive flexibility across development, focusing on interneurons expressing parvalbumin (PV) and somatostatin (SST). The study aims to elucidate how activity in these interneurons influences prefrontal circuit development and function, and how perturbations during critical developmental windows affect adult cognition.