Award
National Institute on Drug Abuse 5R36DA061652-02
Identification of opioid-induced innate immune dysregulation among people living with HIV
Recipient
Oregon Health & Science University, Portland, OR
Award Amount
$53,433.00
Ceiling
$53,433.00
Awarded
March 19, 2026
Identifier
5R36DA061652-02
NIH research grant to study the impact of chronic opioid exposure on immune function in people living with HIV, focusing on monocyte dysregulation and potential therapeutic development.
Description
This research grant aims to determine if chronic opioid exposure disrupts monocyte immunometabolism and function among people living with HIV who also suffer from opioid-use-disorder. The study will reveal the off-target effects of long-term opioid exposure on innate immunity and help develop therapeutics to mitigate opioid-induced monocyte dysregulation.