# NIH Reporter #5F31AI188668-02

Roles for Ets1 in thymic selection and CD8αα IEL development

**Recipient:** University of Chicago

**Award Amount:** $50,114.00
**Ceiling:** $50,114.00

**Awarded:** August 25, 2026

**Identifier:** 5F31AI188668-02

The study examines Ets1's role in T-cell selection and CD8αα IEL development, with the goal of clarifying mechanisms relevant to autoimmune diseases and intestinal health.

### Description

Research project investigating how the transcription factor Ets1 regulates thymic selection and the development and function of CD8αα intraepithelial lymphocytes.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11456620)