Award
NIH Reporter #11382089
Modulation of intracellular lipid access by ATGL determines ferroptosis sensitivity in castration-resistant prostate cancer
Recipient
Not specified
Award Amount
$38,279.00
Ceiling
$38,279.00
Awarded
July 15, 2026
Identifier
11382089
Research project funded by the National Cancer Institute to study the role of ATGL in ferroptosis resistance in castration-resistant prostate cancer, aiming to develop new therapies and biomarkers.
Description
The project focuses on understanding the role of adipose triglyceride lipase (ATGL) in ferroptosis resistance in castration-resistant prostate cancer. It includes a F99 phase aimed at mechanistic studies and a K00 phase focused on metabolism and cancer progression. The project aims to develop novel therapeutic strategies and identify biomarkers for prostate cancer treatment and includes a training plan for the investigator. The project involves collaboration with MD Anderson Cancer Center.