Award
National Institute of Allergy and Infectious Diseases 5R01AI194523-02
Structure and mechanism of the polar tube invasion apparatus from microsporidian parasites
Recipient
Johns Hopkins University, Baltimore, MD
Award Amount
$723,614.00
Ceiling
$723,614.00
Awarded
July 20, 2026
Identifier
5R01AI194523-02
The award supports research to understand the architecture and mechanism of the polar tube used by microsporidian parasites to invade host cells, employing structural biology and microscopy techniques.
Description
This project involves structural and functional analysis of the polar tube invasion machinery in microsporidian parasites, with potential implications for understanding pathogen invasion mechanisms and developing therapeutic strategies.