Award
National Institute of Mental Health 10635413
High-throughput engineering of ligand-selective fluorescent biosensors for detecting endogenous and exogenous opioids
Recipient
National Institute of Mental Health (NIMH)
Award Amount
$2,510,153.00
Ceiling
$2,510,153.00
Awarded
April 13, 2023
Identifier
10635413
Award for developing high-throughput neuropeptide sensors to study opioid-related behaviors, funded by NIH/NIMH.
Description
The project focuses on developing high-throughput platforms for engineering neuropeptide sensors, with applications in neuroscience research and drug screening. The project involves creating large sensor variant libraries, optimizing ligand specificity, and validating sensors in vivo. The project is funded by NIH/NIMH under the RFA-MH-21-175. The project aims to understand neuropeptide dynamics related to behaviors such as stress, anxiety, and opioid abuse.