Award
National Institute on Aging 4R00AG075242-03
Synthetic Reconstruction of Human Chaperone Networks in Yeast Models of Neurodegeneration
Recipient
Temple Univ of the Commonwealth
Award Amount
$249,000.00
Ceiling
$249,000.00
Awarded
May 19, 2026
Identifier
4R00AG075242-03
Award for research on human chaperone networks in yeast models to identify therapeutic targets for neurodegenerative diseases, led by Dr. Edward Barbieri at Temple University.
Description
The project focuses on mapping chaperone networks against proteins associated with neurodegenerative diseases. It involves genetic techniques, yeast models, human cell studies, and biochemistry assays. The goal is to identify therapeutic targets for Alzheimer's disease and related dementias. The project emphasizes training in biochemistry and molecular genetics.