Award
National Institute of Environmental Health Sciences 5R01ES032026-05
Defining the role of in utero estrogenic endocrine disruption on mammary gland stiffness and breast cancer risk
Recipient
Ohio State University
Award Amount
$350,530.00
Ceiling
$350,530.00
Awarded
May 14, 2025
Identifier
5R01ES032026-05
Research project funded by NIEHS to study how in utero exposure to estrogenic endocrine disruptors affects mammary gland stiffness and breast cancer risk, using animal models and molecular biology techniques.
Description
The project focuses on the impact of estrogenic endocrine disrupting compounds (EDCs) on mammary gland development and breast cancer risk. It aims to characterize mechanisms by which EDCs contribute to breast stromal alterations and evaluate their contribution to cancer risk. The project involves animal models, molecular biology, and epigenetic studies and is part of a broader effort to understand environmental factors in cancer development and identify potential biomarkers and therapeutic targets.