Award
National Institute of Neurological Disorders and Stroke 5R01NS128006-03
Clinical Stimulation and Spreading Depolarization
Recipient
University of Virginia, Charlottesville, VA
Award Amount
$403,750.00
Ceiling
$403,750.00
Awarded
July 31, 2025
Identifier
5R01NS128006-03
This NIH-funded research project aims to assess if routine ICU interventions increase the risk of spreading depolarization in patients with large hemispheric strokes, using advanced monitoring techniques to improve stroke management.
Description
The study investigates whether routine ICU interventions in severe stroke patients trigger spreading depolarization (SD), potentially worsening outcomes. Using electrocorticography and physiological monitoring, the research aims to provide insights into SD mechanisms and inform clinical practices.