Award
National Institute of Neurological Disorders and Stroke 7F99NS141403-03
Pneumonia-induced microglial activation causes blood-brain barrier breakdown, astrocyte activation, and tau pathology
Recipient
University of South Florida, Tampa, FL, United States
Award Amount
$34,537.00
Ceiling
$34,537.00
Awarded
December 04, 2025
Identifier
7F99NS141403-03
Research project studying the impact of pneumonia on brain neurovascular function and tau pathology, aiming to develop protective therapies using advanced imaging.
Description
This project investigates how pneumonia causes neurovascular unit dysfunction, focusing on microglia activation leading to blood-brain barrier breakdown and tau pathology. It uses advanced imaging techniques and aims to develop therapies to protect neurovascular function in patients with severe lung infections and migraine disorders.