Award
NIH Reporter #5F30AI179111-03
Population genomics and relapse epidemiology of Plasmodium ovale in sub-Saharan Africa
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL
Award Amount
$55,114.00
Ceiling
$55,114.00
Awarded
August 05, 2026
Identifier
5F30AI179111-03
Research project to study the genomics and relapse epidemiology of Plasmodium ovale malaria in sub-Saharan Africa, aiming to improve understanding and treatment of this parasite to aid malaria elimination and protect American travelers.
Description
The project aims to characterize the population genomics of Plasmodium ovale in sub-Saharan Africa and describe the epidemiology of P. ovale carriage and relapse in Tanzania. It leverages unique access to malaria clinical isolates and a prospective cohort of Tanzanian participants to examine genomics and relapse behaviors of this malaria parasite. The research will inform relapse treatment guidelines and provide genomic details for future research, contributing to malaria elimination efforts including non-falciparum species.