Award
National Institute on Aging 1R21AG089974-01A1
The role of mitochondrial deficits in tauopathy-linked autophagy defects
Recipient
CAI, QIAN
Award Amount
$431,750.00
Ceiling
$431,750.00
Awarded
May 20, 2025
Identifier
1R21AG089974-01A1
Research project funded by the National Institute on Aging to study mitochondrial function and autophagy in tauopathies, aiming to develop novel therapeutic strategies for Alzheimer's disease.
Description
This project investigates the role of mitochondrial Rho GTPase (Miro) in mitochondrial phosphatidylethanolamine (PE) biosynthesis, autophagy, and tau clearance to understand and potentially treat tauopathies including Alzheimer's disease.