Award
National Institute on Aging 1R01AG092766-01A1
Synergistic Effects of Unacylated Ghrelin and Endurance Exercise on Sarcopenia and Mobility Loss
Recipient
Wake Forest University Health Sciences
Award Amount
$599,623.00
Ceiling
$599,623.00
Awarded
January 29, 2026
Identifier
1R01AG092766-01A1
Research project funded by the National Institute on Aging to study the combined effects of unacylated ghrelin and endurance exercise on sarcopenia and mobility loss in aging, with the goal of developing effective interventions.
Description
This project investigates combining endurance exercise with unacylated ghrelin (UnAG) to improve outcomes in older mice by enhancing mitochondrial bioenergetics, neuromuscular junction integrity, muscle mass, and function, aiming to develop a novel, safe, and translatable therapy for sarcopenia.