Award
National Institute of Allergy and Infectious Diseases 5R01AI178726-04
Determinants of Post-Treatment Phenotypes in Lyme Disease
Recipient
Johns Hopkins University, Baltimore, MD, United States
Award Amount
$608,082.00
Ceiling
$608,082.00
Awarded
June 30, 2026
Identifier
5R01AI178726-04
This award funds research to identify clinical, immunologic, and metabolic factors influencing post-treatment Lyme disease outcomes, aiming to develop risk assessment tools and therapeutic strategies.
Description
The proposed study aims to uncover clinical, immunologic, and metabolic determinants of post-treatment Lyme disease (PTLD) and its underlying symptom phenotypes. The goal is to generate fundamental knowledge about why certain patients develop PTLD while others regain their pre-morbid health. Findings may lead to innovative therapeutic strategies and interventions to prevent or reduce symptom burden and functional impact.