Award
NIH Reporter #11239013
Autoinducer-2 and depression
Recipient
University of Miami School of Medicine
Award Amount
$524,579.00
Ceiling
$524,579.00
Awarded
December 01, 2025
Identifier
11239013
Research project funded by NIMH to study the impact of bacterial autoinducer-2 on stress and depression, focusing on neurobiological mechanisms and gut-brain axis.
Description
This project investigates the role of quorum sensing molecules, specifically autoinducer-2 (AI-2), in stress-related behaviors and depression. It aims to determine how stress modulates bacterial AI-2 production and its impact on neurobiology, including immune responses and gut-brain axis interactions.