Award
NIH Reporter #2R01EB033172-05
Next-Gen Fluorescent Indicators for Imaging Synaptic Zinc in Cortical Sound Processing
Recipient
University of Virginia, Charlottesville, VA
Award Amount
$657,359.00
Ceiling
$657,359.00
Awarded
August 21, 2026
Identifier
2R01EB033172-05
Award to University of Virginia for developing advanced fluorescent zinc indicators to study synaptic zinc dynamics in auditory processing, aiming to understand neurological disorder connections.
Description
Development of next-generation genetically encoded fluorescent zinc indicators (GEZIs) for in vivo imaging of synaptic Zn2+ dynamics to map how synaptic Zn2+ release contributes to auditory adaptation mechanisms using intensity- and lifetime-based sensors for precise, quantitative imaging.