Award
National Institute on Aging 1R21AG087430-01A1
Understanding nuclear compensation to mitochondrial variation, dysfunction, and disease in a new evolutionary mutant model
Recipient
University of Kansas Lawrence
Award Amount
$399,766.00
Ceiling
$399,766.00
Awarded
December 23, 2024
Identifier
1R21AG087430-01A1
A research project funded by the National Institute on Aging to study nuclear compensation mechanisms to mitochondrial variation and dysfunction using an evolutionary mutant model in threespine stickleback fish.
Description
The project focuses on mitochondrial-nuclear interactions, genetic variation, and adaptation in threespine stickleback fish. The project aims to study how nuclear genomes compensate for mitochondrial variation and dysfunction, leveraging natural populations with high mitogenomic divergence. The project will utilize publicly available sequencing data and preserved specimens.